Breakage study

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Dr. Osama K Zaki                    

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Breakage study
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Characteristic Tri-radiate figures in a case of Fanconi anemia

Several disorders are characterized by increase in the level of chromosome breakage. This may occur spontaneously during routine cell  culture or more commonly after stressing the dividing cells by various techniques. 

 

Chromosome breakage syndromes

bulletFanconi Anemia
bulletAtaxia Telangiectasia
bulletBloom Syndrome
bulletXeroderma Pigmentosa
bulletOther less common breakage syndromes

 

 

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