Solid tumors

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Dr. Osama K Zaki                    

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Bone marrow
Peripheral Blood
Solid tumors

 

 

Cancer cytogenetic of Solid tumors

    Several non hematological solid tumors have been shown to be associated with a specific pattern of chromosomal abnormality.  This is especially true for cases with childhood tumors such as Retinoblastoma, Wilm's tumor.  A long list of chromosomal aberrations in association with malignancy is now available. Many of those aberrations are "private"  i.e. they do not occur, frequently, in association with the specific tumor phenotype. However, cytogenetic study is still a sensitive  tool for the diagnosis and follow up of some non hematological  malignancies. 

Indications

bulletTo determine the nature of tumor especially in non-differentiated tumors.
bulletTo  predict the prognosis .
bulletTo monitor  cases  for  karyotype evolution .
bulletTo detect recurrences after chemotherapy.

Analytic time:

Cases requiring short term culture : usually 5-8 days

Cases requiring long term culture :  2-4 wks depending on the rate of spontaneous growth of cultured cells. 

 

 

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