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FOR IMMEDIATE RELEASE
Reviews of Literature
By Dr. Osama Zaki
June,31,2001 -- The following is a brief list of the most recent
publications that came to our attention during the last months. To
read the topics or their abstracts, just click the underlined link
| Cell
proliferation and protein synthesis as initial factors in determination of
axial polarity - Development
Growth & Differentiation |
| The rate of cell proliferation
relative to that of protein synthesis appears to have an initial role in
establishment of axial polarities in developing animal embryos. An
increase in this ratio leads to anterior or dorsal differentiation, while
reduction allows posterior or ventral differentiation in a number of
organisms. The role that various growth factors play in the regulation of
proliferation and protein synthesis is examined... |
| Foot
problems in Turner's syndrome
- Journal of Pediatrics |
| In a randomized, prospective
study, data were collected on 23 girls with Turner's syndrome (TS) and
an age- and sex-matched control group of 47 girls in order to document
foot problems and to establish their cause. History revealed that 6
(26%) girls with TS had problems with ingrowing toenails compared with
none of the control subjects. Compared with the control subjects, girls
with TS showed a significantly increased incidence of short, broad feet;
hyperextension of the great toes at the interphalangeal joint; toe nail
involution; inflammation of the periungual tissues; and intermittent
lymphedema... |
| Ethical
Issues With Genetic Testing in Pediatrics -
Pediatrics |
| Advances in genetic research
promise great strides in the diagnosis and treatment of many childhood
diseases. However, emerging genetic technology often enables testing and
screening before the development of definitive treatment or preventive
measures. In these circumstances, careful consideration must be given to
testing and screening of children to ensure that use of this technology
promotes the best interest of the child... |
| Human
Molecular Embryogenesis: An Overview
- Pediatric and Developmental Pathology |
| Molecular embryology is a
rapidly evolving field of great complexity. This overview is primarily for
the newcomer to this field, in an attempt to demystify the processes by
which a human single-celled zygote eventually forms an embryo... |
| Feasibility
of Collecting Buccal Cell DNA by Mail in a Cohort Study
- Cancer Epidemiology, Biomarkers & Prevention |
| This study demonstrates
under field conditions that it is possible, using a mail mouthwash
protocol, to obtain genomic DNA adequate for PCR-RFLP-based genotyping
from a large number of individuals participating in a multiethnic cohort
study. It also shows that it is possible to almost double the amount of
DNA collected by requesting two samples instead of one, without
affecting the response rate... |
| AAP
Statement on Molecular Genetic Testing in Children -
American Family Physician |
| The Committee on Genetics of
the American Academy of Pediatrics (AAP) has issued a position statement
on molecular genetic testing in pediatric patients. The AAP statement
appears in the December 2000 issue of Pediatrics. For decades, many types
of diagnostic and carrier testing for genetic disorders have been
available, but the use of molecular methods is a relatively recent
phenomenon... |
| Collection
of Genomic DNA from Adults in Epidemiological Studies by Buccal
Cytobrush and Mouthwash
- Cancer Epidemiology, Biomarkers & Prevention |
| We have shown that a single
self-collected 10-ml Scope mouthwash sample (14.3 wt% alcohol) sent by
mail at room temperature provides substantially larger amounts of human
genomic DNA than two self-collected cytobrush samples sent by mail at
room temperature without a transport medium. Although most (>93%) of
the mouthwash phenol-chloroform DNA extracts and only 60% of the
cytobrush phenol-chloroform DNA extracts contained high molecular weight
DNA (>23 kb), all extracts by either method were adequate for a wide
range of PCR-based assays |
Your contribution with new items, local or international publications will be
a great addition to this page. to send a paper or other information please contact
us
For More Information Contact:
The Medical Genetics Center
53 Atlas Buildings, Nasr City,East Sixth Area, Cairo, Egypt
Tel: +(202) 270-0366 / + (202) 273-1933
FAX: +(202) 240-2020
Internet: support@medical-genetics.net
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